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Glyco-modification of protein with O-cyanate chain-end functionalized glycopolymer via isourea bond formation

Glycoengineering aimed at addition of carbohydrates to proteins is an attractive approach to alter pharmacokinetic properties of proteins such as enhancing stability and prolonging the duration of action. We report a novel protein glyco-modification of BSA and recombinant thrombomodulin with O-cyana...

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Veröffentlicht in:J Carbohydr Chem
Hauptverfasser: Gruzdys, Valentinas, Zhang, Hailong, Sun, Xue-Long
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235998/
https://ncbi.nlm.nih.gov/pubmed/25419041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07328303.2014.922189
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