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End-to-end distance distributions and intrachain diffusion constants in unfolded polypeptide chains indicate intramolecular hydrogen bond formation

Characterization of the unfolded state is essential for the understanding of the protein folding reaction. We performed time-resolved FRET measurements to gain information on the dimensions and the internal dynamics of unfolded polypeptide chains. Using an approach based on global analysis of data o...

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Detalhes bibliográficos
Main Authors: Möglich, Andreas, Joder, Karin, Kiefhaber, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567890/
https://ncbi.nlm.nih.gov/pubmed/16894178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604748103
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