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Glyco-modification of protein with O-cyanate chain-end functionalized glycopolymer via isourea bond formation

Glycoengineering aimed at addition of carbohydrates to proteins is an attractive approach to alter pharmacokinetic properties of proteins such as enhancing stability and prolonging the duration of action. We report a novel protein glyco-modification of BSA and recombinant thrombomodulin with O-cyana...

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Detalhes bibliográficos
Publicado no:J Carbohydr Chem
Main Authors: Gruzdys, Valentinas, Zhang, Hailong, Sun, Xue-Long
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235998/
https://ncbi.nlm.nih.gov/pubmed/25419041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07328303.2014.922189
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