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Activation of PI3K and R-Ras Signaling Promotes the Extension of Sensory Axons on Inhibitory Chondroitin Sulfate Proteoglycans

Chondroitin sulfate proteoglycans (CSPGs) are extracellular inhibitors of axon extension and plasticity, and cause growth cones to exhibit dystrophic behaviors. Phosphoinositide 3-kinase (PI3K) is a lipid kinase activated by axon growth promoting signals. In this study we used embryonic chicken dors...

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Detalhes bibliográficos
Publicado no:Dev Neurobiol
Principais autores: Silver, Lee, Michael, James V., Goldfinger, Lawrence E., Gallo, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235675/
https://ncbi.nlm.nih.gov/pubmed/24578264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22174
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