Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling

Chondroitin sulfate proteoglycans (CSPGs) are upregulated after CNS lesions, where they inhibit axon regeneration. In order for axon growth and regeneration to occur, surface integrin receptors must interact with surrounding extracellular matrix molecules. We have explored the hypothesis that CSPGs...

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Hlavní autoři: Tan, Chin Lik, Kwok, Jessica C. F., Patani, Rickie, ffrench-Constant, Charles, Chandran, Siddharthan, Fawcett, James W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2011
Témata:
Brief Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116378/
https://ncbi.nlm.nih.gov/pubmed/21525268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0008-11.2011
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