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Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling

Chondroitin sulfate proteoglycans (CSPGs) are upregulated after CNS lesions, where they inhibit axon regeneration. In order for axon growth and regeneration to occur, surface integrin receptors must interact with surrounding extracellular matrix molecules. We have explored the hypothesis that CSPGs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tan, Chin Lik, Kwok, Jessica C. F., Patani, Rickie, ffrench-Constant, Charles, Chandran, Siddharthan, Fawcett, James W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116378/
https://ncbi.nlm.nih.gov/pubmed/21525268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0008-11.2011
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