Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling

Chondroitin sulfate proteoglycans (CSPGs) are upregulated after CNS lesions, where they inhibit axon regeneration. In order for axon growth and regeneration to occur, surface integrin receptors must interact with surrounding extracellular matrix molecules. We have explored the hypothesis that CSPGs...

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Bibliographic Details
Main Authors: Tan, Chin Lik, Kwok, Jessica C. F., Patani, Rickie, ffrench-Constant, Charles, Chandran, Siddharthan, Fawcett, James W.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2011
Subjects:
Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116378/
https://ncbi.nlm.nih.gov/pubmed/21525268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0008-11.2011
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