Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling

Chondroitin sulfate proteoglycans (CSPGs) are upregulated after CNS lesions, where they inhibit axon regeneration. In order for axon growth and regeneration to occur, surface integrin receptors must interact with surrounding extracellular matrix molecules. We have explored the hypothesis that CSPGs...

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Bibliografiska uppgifter
Huvudupphovsmän: Tan, Chin Lik, Kwok, Jessica C. F., Patani, Rickie, ffrench-Constant, Charles, Chandran, Siddharthan, Fawcett, James W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2011
Ämnen:
Brief Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116378/
https://ncbi.nlm.nih.gov/pubmed/21525268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0008-11.2011
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