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Role of solvation in pressure-induced helix stabilization

In contrast to the well-known destabilization of globular proteins by high pressure, recent work has shown that pressure stabilizes the formation of isolated α-helices. However, all simulations to date have obtained a qualitatively opposite result within the experimental pressure range. We show that...

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Détails bibliographiques
Publié dans:J Chem Phys
Auteurs principaux: Best, Robert B., Miller, Cayla, Mittal, Jeetain
Format: Artigo
Langue:Inglês
Publié: American Institute of Physics 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235627/
https://ncbi.nlm.nih.gov/pubmed/25494793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4901112
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