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Temperature-dependent solvation modulates the dimensions of disordered proteins

For disordered proteins, the dimensions of the chain are an important property that is sensitive to environmental conditions. We have used single-molecule Förster resonance energy transfer to probe the temperature-induced chain collapse of five unfolded or intrinsically disordered proteins. Because...

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Main Authors: Wuttke, René, Hofmann, Hagen, Nettels, Daniel, Borgia, Madeleine B., Mittal, Jeetain, Best, Robert B., Schuler, Benjamin
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986154/
https://ncbi.nlm.nih.gov/pubmed/24706910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313006111
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