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Dependence of Protein Folding Stability and Dynamics on the Density and Composition of Macromolecular Crowders
We investigate the effect of macromolecular crowding on protein folding, using purely repulsive crowding particles and a self-organizing polymer model of protein folding. We find that the variation in folding stability with crowder size for typical α-, β-, and α/β-proteins is well described by an ad...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808496/ https://ncbi.nlm.nih.gov/pubmed/20338853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.10.009 |
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