TRF2 and lamin A/C interact to facilitate the functional organization of chromosome ends

Telomeres protect the ends of linear genomes, and the gradual loss of telomeres is associated with cellular ageing. Telomere protection involves the insertion of the 3′ overhang facilitated by telomere repeat-binding factor 2 (TRF2) into telomeric DNA, forming t-loops. We present evidence suggesting...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Wood, Ashley M., Danielsen, Jannie M. Rendtlew, Lucas, Catherine A., Rice, Ellen L., Scalzo, David, Shimi, Takeshi, Goldman, Robert D., Smith, Erica D., Le Beau, Michelle M., Kosak, Steven T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235626/
https://ncbi.nlm.nih.gov/pubmed/25399868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6467
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