Human neutrophil elastase modulates platelet function by limited proteolysis of membrane glycoproteins.

During blood coagulation human polymorphonuclear leukocytes release elastase in amounts that can exceed 100 nmol/liter. We therefore studied the effect of elastase on platelet structure and function. Physiologic concentrations of elastase specifically inhibited thrombin-induced platelet aggregation...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Brower, M S, Levin, R I, Garry, K
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1985
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3156151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111744
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