Human neutrophil elastase modulates platelet function by limited proteolysis of membrane glycoproteins.
During blood coagulation human polymorphonuclear leukocytes release elastase in amounts that can exceed 100 nmol/liter. We therefore studied the effect of elastase on platelet structure and function. Physiologic concentrations of elastase specifically inhibited thrombin-induced platelet aggregation...
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| Publicado no: | J Clin Invest |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3156151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111744 |
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