Human neutrophil elastase modulates platelet function by limited proteolysis of membrane glycoproteins.

During blood coagulation human polymorphonuclear leukocytes release elastase in amounts that can exceed 100 nmol/liter. We therefore studied the effect of elastase on platelet structure and function. Physiologic concentrations of elastase specifically inhibited thrombin-induced platelet aggregation...

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Bibliografske podrobnosti
Main Authors: Brower, M S, Levin, R I, Garry, K
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC423550/
https://ncbi.nlm.nih.gov/pubmed/3156151
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