Chargement en cours...

Thiourea-Catalyzed Enantioselective Addition of Indoles to Pyrones: Alkaloid Cores with Quaternary Carbons

[Image: see text] We report the development of a catalytic method for the enantioselective addition of indoles to pyrone-derived electrophiles. Arylpyrrolidino-derived thioureas catalyze the addition with high stereoselectivity in the presence of catalytic quantities of an achiral Brønsted acid. The...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Yeung, Charles S., Ziegler, Robert E., Porco, John A., Jacobsen, Eric N.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235369/
https://ncbi.nlm.nih.gov/pubmed/25213353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja508523g
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!