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SV40 late protein VP4 forms toroidal pores to disrupt membranes for viral release

Nonenveloped viruses are generally released from the cell by the timely lysis of host cell membranes. SV40 has been used as a model virus for the study of the lytic nonenveloped virus life cycle. The expression of SV40 VP4 at later times during infection is concomitant with cell lysis. To investigat...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Raghava, Smita, Giorda, Kristina M., Romano, Fabian B., Heuck, Alejandro P., Hebert, Daniel N.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235334/
https://ncbi.nlm.nih.gov/pubmed/23651212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400036z
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