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The SV40 Late Protein VP4 Is a Viroporin that Forms Pores to Disrupt Membranes for Viral Release

Nonenveloped viruses are generally released by the timely lysis of the host cell by a poorly understood process. For the nonenveloped virus SV40, virions assemble in the nucleus and then must be released from the host cell without being encapsulated by cellular membranes. This process appears to inv...

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Bibliographic Details
Main Authors: Raghava, Smita, Giorda, Kristina M., Romano, Fabian B., Heuck, Alejandro P., Hebert, Daniel N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128117/
https://ncbi.nlm.nih.gov/pubmed/21738474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002116
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