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The Viroporin Activity of the Minor Structural Proteins VP2 and VP3 Is Required for SV40 Propagation

For nonenveloped viruses such as Simian Virus 40, the mechanism used to translocate viral components across membranes is poorly understood. Previous results indicated that the minor structural proteins, VP2 and VP3, might act as membrane proteins during infection. Here, purified VP2 and VP3 were fou...

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Detalhes bibliográficos
Main Authors: Giorda, Kristina M., Raghava, Smita, Zhang, Macy W., Hebert, Daniel N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554919/
https://ncbi.nlm.nih.gov/pubmed/23223228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.428425
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