A nonantigenic covalent streptokinase-polyethylene glycol complex with plasminogen activator function.
A series of new, covalent polyethylene glycol (PEG)-streptokinase adducts were synthesized and characterized. PEGs with average molecular weights of 2,000, 4,000, and 5,000 were activated with carbonyldiimidazole and coupled to the protein under standardized reaction conditions. Steady-state kinetic...
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| Publicado en: | J Clin Invest |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1985
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3156148/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111715 |
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