A nonantigenic covalent streptokinase-polyethylene glycol complex with plasminogen activator function.

A series of new, covalent polyethylene glycol (PEG)-streptokinase adducts were synthesized and characterized. PEGs with average molecular weights of 2,000, 4,000, and 5,000 were activated with carbonyldiimidazole and coupled to the protein under standardized reaction conditions. Steady-state kinetic...

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Bibliografiske detaljer
Main Authors: Rajagopalan, S, Gonias, S L, Pizzo, S V
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC423508/
https://ncbi.nlm.nih.gov/pubmed/3156148
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