A nonantigenic covalent streptokinase-polyethylene glycol complex with plasminogen activator function.

A series of new, covalent polyethylene glycol (PEG)-streptokinase adducts were synthesized and characterized. PEGs with average molecular weights of 2,000, 4,000, and 5,000 were activated with carbonyldiimidazole and coupled to the protein under standardized reaction conditions. Steady-state kinetic...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Rajagopalan, S, Gonias, S L, Pizzo, S V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3156148/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111715
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