Gemcitabine as a molecular targeting agent that blocks the Akt cascade in platinum-resistant ovarian cancer

BACKGROUND: Gemcitabine (2′, 2′ –difluorodeoxycytidine) is one of many nonplatinum drugs that exhibit activity in recurrent, platinum-resistant ovarian cancer. However, the molecular mechanisms by which Gemcitabine treatment inhibits the proliferation of platinum-resistant ovarian cancer cells still...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Ovarian Res
Main Authors: Kawaguchi, Hiroshi, Terai, Yoshito, Tanabe, Akiko, Sasaki, Hiroshi, Takai, Masaaki, Fujiwara, Satoe, Ashihara, Keisuke, Tanaka, Yoshimichi, Tanaka, Tomohito, Tsunetoh, Satoshi, Kanemura, Masanori, Ohmichi, Masahide
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234938/
https://ncbi.nlm.nih.gov/pubmed/24713296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-7-38
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