GPR30 regulates the EGFR-Akt cascade and predicts lower survival in patients with ovarian cancer

OBJECTIVES: G protein-coupled receptor 30 (GPR30) is a 7-transmembrane estrogen receptor that functions alongside traditional estrogen receptors to regulate the cellular responses to estrogen. Recent studies suggest that GPR30 expression is associated with a poor prognosis, and that this is due to t...

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Bibliografiska uppgifter
Huvudupphovsmän: Fujiwara, Satoe, Terai, Yoshito, Kawaguchi, Hiroshi, Takai, Masaaki, Yoo, Saha, Tanaka, Yoshimichi, Tanaka, Tomohito, Tsunetoh, Satoshi, Sasaki, Hiroshi, Kanemura, Masanori, Tanabe, Akiko, Yamashita, Yoshiki, Ohmichi, Masahide
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543193/
https://ncbi.nlm.nih.gov/pubmed/23163984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-5-35
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