Progressive Genomic Instability in the Nup98-HoxD13 Model of MDS Correlates with Loss of the PIG-A Gene Product()()

The Nup98-HoxD13 (NHD13) fusion gene was identified in a patient with therapy-related myelodysplastic syndrome (MDS). When transgenically expressed in hematopoietic cells, mice faithfully recapitulate human disease with serial progression from peripheral blood (PB) cytopenias and increased bone marr...

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Bibliographic Details
Published in:Neoplasia
Main Authors: Byrne, Michael, Bennett, Richard L., Cheng, Xiaodong, Stratford May, W.
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234872/
https://ncbi.nlm.nih.gov/pubmed/25220590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.07.004
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