Optimizing Single Agent Panitumumab Therapy in Pre-Treated Advanced Colorectal Cancer()()

PURPOSE: To improve the selection of advanced colorectal cancer patients to panitumumab by optimizing the assessment of RAS (KRAS-NRAS) mutations. EXPERIMENTAL DESIGN: Using a centralized pyrosequencing RAS assay, we analyzed the tumors of 94 patients, wild-type for KRAS mutations (codons 12 to 13)...

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Publicado en:Neoplasia
Autores principales: Gasparini, Giampietro, Buttitta, Fiamma, D'Andrea, Mario Rosario, Tumolo, Salvatore, Buonadonna, Angela, Pavese, Ida, Cordio, Stefano, De Tursi, Michele, Mosconi, Stefania, Stumbo, Luciano, Felicioni, Lara, Marchetti, Antonio
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234870/
https://ncbi.nlm.nih.gov/pubmed/25246275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.08.002
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