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Optimizing Single Agent Panitumumab Therapy in Pre-Treated Advanced Colorectal Cancer()()
PURPOSE: To improve the selection of advanced colorectal cancer patients to panitumumab by optimizing the assessment of RAS (KRAS-NRAS) mutations. EXPERIMENTAL DESIGN: Using a centralized pyrosequencing RAS assay, we analyzed the tumors of 94 patients, wild-type for KRAS mutations (codons 12 to 13)...
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Publicado no: | Neoplasia |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Neoplasia Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4234870/ https://ncbi.nlm.nih.gov/pubmed/25246275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.08.002 |
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