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Spiroacetal Formation through Telescoped Cycloaddition and Carbon–Hydrogen Bond Functionalization: Total Synthesis of Bistramide A

Spiroacetals can be formed through a one-pot sequence of a hetero Diels-Alder reaction, an oxidative carbon–hydrogen bond cleavage, and an acid treatment. This convergent approach expedites access to a complex molecular subunit that is present in numerous biologically active structures. The utility...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Han, Xun, Floreancig, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234310/
https://ncbi.nlm.nih.gov/pubmed/25196585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201406819
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