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Total Synthesis of Swinholide A: An Exposition in Hydrogen-Mediated C-C Bond Formation
Diverse hydrogen-mediated C-C couplings enable construction of the actin-binding marine polyketide swinholide A in only 15 steps (LLS); roughly half the steps required in two prior total syntheses. The redox-economy, chemo- and stereoselectivity embodied by this new class of C-C couplings are shown...
Gardado en:
| Publicado en: | J Am Chem Soc |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5096380/ https://ncbi.nlm.nih.gov/pubmed/27779393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10645 |
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