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Catalysis of Heterocyclic Azadiene Cycloaddition Reactions by Solvent Hydrogen Bonding: Concise Total Synthesis of Methoxatin

Although examined for decades, no general approach to catalysis of the inverse electron demand Diels–Alder reactions of heterocyclic azadienes has been introduced. Typically, additives such as Lewis acids lead to non-productive consumption of the electron-rich dienophiles without productive activati...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Glinkerman, Christopher M., Boger, Dale L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042865/
https://ncbi.nlm.nih.gov/pubmed/27571404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b05438
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