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Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms.

Nitric oxide (NO) produces rapid osteoclast detachment and contraction in vitro, and this effect is accompanied by a profound inhibition of bone resorption. Work by others has confirmed these findings in vivo: inhibition of NO synthase [NOS; L-arginine, NADPH: oxygen oxidoreductase (NO-forming), EC...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Brandi, M L, Hukkanen, M, Umeda, T, Moradi-Bidhendi, N, Bianchi, S, Gross, S S, Polak, J M, MacIntyre, I
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42337/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7535933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2954
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