Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms.

Nitric oxide (NO) produces rapid osteoclast detachment and contraction in vitro, and this effect is accompanied by a profound inhibition of bone resorption. Work by others has confirmed these findings in vivo: inhibition of NO synthase [NOS; L-arginine, NADPH: oxygen oxidoreductase (NO-forming), EC...

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Autors principals: Brandi, M L, Hukkanen, M, Umeda, T, Moradi-Bidhendi, N, Bianchi, S, Gross, S S, Polak, J M, MacIntyre, I
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC42337/
https://ncbi.nlm.nih.gov/pubmed/7535933
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