Potentiation of osteoclast bone-resorption activity by inhibition of nitric oxide synthase.

We have examined the effects of modulating nitric oxide (NO) levels on osteoclast-mediated bone resorption in vitro and the effects of nitric oxide synthase (NOS) inhibitors on bone mineral density in vivo. Diaphorase-based histochemical staining for NOS activity of bone sections or highly enriched...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kasten, T P, Collin-Osdoby, P, Patel, N, Osdoby, P, Krukowski, M, Misko, T P, Settle, S L, Currie, M G, Nickols, G A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7513424/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.3569
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