Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway

BACKGROUND: Recent studies have demonstrated a protective effect of osteocalcin (OCN) on glucose homeostasis and metabolic syndrome. However, its role in vascular function remains unknown. This study investigated the contribution of OCN to the pathogenesis of endothelial dysfunction in the thoracic...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Dou, Jianxin, Li, Huating, Ma, Xiaojing, Zhang, Mingliang, Fang, Qichen, Nie, Meiyun, Bao, Yuqian, Jia, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233640/
https://ncbi.nlm.nih.gov/pubmed/24708830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-74
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