Nafamostat mesilate promotes endothelium-dependent vasorelaxation via the Akt-eNOS dependent pathway

Nafamostat mesilate (NM), a synthetic serine protease inhibitor, has anticoagulant and anti-inflammatory properties. The intracellular mediator and external anti-inflammatory external signal in the vascular wall have been reported to protect endothelial cells, in part due to nitric oxide (NO) produc...

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Veröffentlicht in:Korean J Physiol Pharmacol
Hauptverfasser: Choi, Sujeong, Kwon, Hyon-Jo, Song, Hee-Jung, Choi, Si Wan, Nagar, Harsha, Piao, Shuyu, Jung, Saet-byel, Jeon, Byeong Hwa, Kim, Dong Woon, Kim, Cuk-Seong
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Physiological Society and The Korean Society of Pharmacology 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015001/
https://ncbi.nlm.nih.gov/pubmed/27610041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2016.20.5.539
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