Multifunctional Core/Shell Nanoparticles Cross-linked Polyetherimide-folic Acid as Efficient Notch-1 siRNA Carrier for Targeted Killing of Breast Cancer

In gene therapy, how genetic therapeutics can be efficiently and safely delivered into target tissues/cells remains a major obstacle to overcome. To address this issue, nanoparticles consisting of non-covalently coupled polyethyleneimine (PEI) and folic acid (FA) to the magnetic and fluorescent core...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Hong, Li, Ying, Li, Tingting, Xu, Min, Chen, Yin, Wu, Chunhui, Dang, Xitong, Liu, Yiyao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233336/
https://ncbi.nlm.nih.gov/pubmed/25400232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07072
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