Polyetherimide-grafted Fe(3)O(4)@SiO(2) nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging

Engineering a safe and high-efficiency delivery system for efficient RNA interference is critical for successful gene therapy. In this study, we designed a novel nanocarrier system of polyethyleneimine (PEI)-modified Fe(3)O(4)@SiO(2), which allows high efficient loading of VEGF small hairpin (sh)RNA...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Li, Tingting, Shen, Xue, Chen, Yin, Zhang, Chengchen, Yan, Jie, Yang, Hong, Wu, Chunhui, Zeng, Hongjun, Liu, Yiyao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495783/
https://ncbi.nlm.nih.gov/pubmed/26170664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S85095
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