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Cardiac P2X purinergic receptors as a new pathway for increasing Na(+) entry in cardiac myocytes

P2X4 receptors (P2X4Rs) are ligand-gated ion channels capable of conducting cations such as Na(+). Endogenous cardiac P2X4R can mediate ATP-activated current in adult murine cardiomyocytes. In the present study, we tested the hypothesis that cardiac P2X receptors can induce Na(+) entry and modulate...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Shen, Jian-Bing, Yang, Ronghua, Pappano, Achilles, Liang, Bruce T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233301/
https://ncbi.nlm.nih.gov/pubmed/25239801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00553.2014
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