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P2X4 receptor–eNOS signaling pathway in cardiac myocytes as a novel protective mechanism in heart failure

We have demonstrated using immunoprecipitation and immunostaining a novel physical association of the P2X4 receptor (P2X4R), a ligand-gated ion channel, with the cardioprotective, calcium-dependent enzyme endothelial nitric oxide synthase (eNOS). Treatment of murine ventricular myocytes with the P2X...

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Detalhes bibliográficos
Main Authors: Ronghua Yang, Dardan Beqiri, Jian-Bing Shen, John M. Redden, Kimberly Dodge-Kafka, Kenneth A. Jacobson, Bruce T. Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015-01-01
Colecção:Computational and Structural Biotechnology Journal
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2001037014000439
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