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Interleukin-6 amplifies glucagon secretion: coordinated control via the brain and pancreas
Inappropriate glucagon secretion contributes to hyperglycemia in inflammatory disease. Previous work implicates the proinflammatory cytokine interleukin-6 (IL-6) in glucagon secretion. IL-6-KO mice have a blunted glucagon response to lipopolysaccharide (LPS) that is restored by intravenous replaceme...
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| 出版年: | Am J Physiol Endocrinol Metab |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233256/ https://ncbi.nlm.nih.gov/pubmed/25205821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00343.2014 |
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