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Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects

While it is currently estimated that 40–50% of eukaryotic proteins are phosphorylated, little is known about the frequency and local effects of phosphorylation near pharmaceutical inhibitor binding sites. In this study, we investigated how frequently phosphorylation may affect the binding of drug in...

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Publicat a:Proteins
Autors principals: Smith, Kyle P., Gifford, Kathleen M., Waitzman, Joshua S., Rice, Sarah E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233198/
https://ncbi.nlm.nih.gov/pubmed/24833420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24605
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