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Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects

While it is currently estimated that 40–50% of eukaryotic proteins are phosphorylated, little is known about the frequency and local effects of phosphorylation near pharmaceutical inhibitor binding sites. In this study, we investigated how frequently phosphorylation may affect the binding of drug in...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Smith, Kyle P., Gifford, Kathleen M., Waitzman, Joshua S., Rice, Sarah E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233198/
https://ncbi.nlm.nih.gov/pubmed/24833420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24605
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