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Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects

While it is currently estimated that 40–50% of eukaryotic proteins are phosphorylated, little is known about the frequency and local effects of phosphorylation near pharmaceutical inhibitor binding sites. In this study, we investigated how frequently phosphorylation may affect the binding of drug in...

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Détails bibliographiques
Publié dans:Proteins
Auteurs principaux: Smith, Kyle P., Gifford, Kathleen M., Waitzman, Joshua S., Rice, Sarah E.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233198/
https://ncbi.nlm.nih.gov/pubmed/24833420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24605
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