The Notch pathway inhibits TGF-β signaling in breast cancer through HEYL-mediated crosstalk

Acquired resistance to transforming growth factor-β (TGF-β) is a key step in the early stages of tumorigenesis. Mutations in TGF-β signaling components are rare, and little is known about development of resistance in breast cancer. On the other hand, an activated Notch pathway is known to play a sub...

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Publicat a:Cancer Res
Autors principals: Han, Liangfeng, Diehl, Adam, Nguyen, Nguyen, Korangath, Preethi, Teo, Weiwen, Cho, Soonweng, Kominsky, Scott, Huso, David L., Feigenbaum, Lionel, Rein, Alan, Argani, Pedram, Landberg, Goran, Gessler, Manfred, Sukumar, Saraswati
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233182/
https://ncbi.nlm.nih.gov/pubmed/25217524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0816
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