Plk1 inhibition enhances the efficacy of androgen signaling blockade in castration-resistant prostate cancer

Prostate cancer (PCa) is thought to be driven by oxidative stress, lipid metabolism, androgen receptor (AR) signaling and activation of the PI3K/AKT/mTOR pathway, but it is uncertain how they may become coordinated during progression to castration-resistant disease which remains incurable. The mitot...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Zhang, Zhe, Hou, Xianzeng, Shao, Chen, Li, Junjie, Cheng, Ji-Xin, Kuang, Shihuan, Ahmad, Nihal, Ratliff, Timothy, Liu, Xiaoqi
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233180/
https://ncbi.nlm.nih.gov/pubmed/25252916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1916
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