The renin-angiotensin system mediates epidermal growth factor receptor-vitamin D receptor cross-talk in colitis-associated colon cancer

PURPOSE: We previously showed that epidermal growth factor receptor (EGFR) promotes tumorigenesis in the azoxymethane/dextran sulfate sodium (AOM/DSS) model, whereas vitamin D (VD) suppresses tumorigenesis. EGFR-vitamin D receptor (VDR) interactions, however, are incompletely understood. VD inhibits...

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Pubblicato in:Clin Cancer Res
Autori principali: Dougherty, Urszula, Mustafi, Reba, Sadiq, Farhana, Almoghrabi, Anas, Mustafi, Devkumar, Kreisheh, Maggi, Sundaramurthy, Sumana, Liu, Weicheng, Konda, Vani J., Pekow, Joel, Khare, Sharad, Hart, John, Joseph, Loren, Wyrwicz, Alice, Karczmar, Gregory S., Li, Yan Chun, Bissonnette, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233154/
https://ncbi.nlm.nih.gov/pubmed/25212605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0209
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