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Tumor suppressors miR-143 and miR-145 and predicted target proteins API5, ERK5, K-RAS, and IRS-1 are differentially expressed in proximal and distal colon

The colon differs regionally in local luminal environment, excretory function, and gene expression. Polycistronic microRNA (miR)-143 and miR-145 are downregulated early in colon cancer. We asked if these microRNAs (miRNAs) might be differentially expressed in the proximal vs. the distal colon, contr...

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書誌詳細
出版年:Am J Physiol Gastrointest Liver Physiol
主要な著者: Pekow, Joel, Meckel, Katherine, Dougherty, Urszula, Butun, Fatma, Mustafi, Reba, Lim, John, Crofton, Charis, Chen, Xindi, Joseph, Loren, Bissonnette, Marc
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312953/
https://ncbi.nlm.nih.gov/pubmed/25477374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00208.2014
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