EGFR signals down-regulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: Role of G1 regulators

Epidermal growth factor receptors (EGFR) contribute to colonic tumorigenesis in experimental models of colon cancer. We previously showed that EGFR was also required for colonic tumor promotion by Western diet. The goal of this study was to identify EGFR-regulated microRNAs that contribute to diet-p...

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Autores principales: Zhu, Hongyan, Dougherty, Urszula, Robinson, Victoria, Mustafi, Reba, Pekow, Joel, Kupfer, Sonia, Li, Yan Chun, Hart, John, Goss, Kathleen, Fichera, Alessandro, Joseph, Loren, Bissonnette, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819602/
https://ncbi.nlm.nih.gov/pubmed/21653642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0531
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