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EGFR signals down-regulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: Role of G1 regulators

Epidermal growth factor receptors (EGFR) contribute to colonic tumorigenesis in experimental models of colon cancer. We previously showed that EGFR was also required for colonic tumor promotion by Western diet. The goal of this study was to identify EGFR-regulated microRNAs that contribute to diet-p...

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Détails bibliographiques
Auteurs principaux: Zhu, Hongyan, Dougherty, Urszula, Robinson, Victoria, Mustafi, Reba, Pekow, Joel, Kupfer, Sonia, Li, Yan Chun, Hart, John, Goss, Kathleen, Fichera, Alessandro, Joseph, Loren, Bissonnette, Marc
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819602/
https://ncbi.nlm.nih.gov/pubmed/21653642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0531
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