SOX4 inhibits GBM cell growth and induces G0/G1 cell cycle arrest through Akt-p53 axis

BACKGROUND: SOX4 is a transcription factor required for tissue development and differentiation in vertebrates. Overexpression of SOX4 has been reported in many cancers including glioblastoma multiforme (GBM), however, the underlying mechanism of actions has not been studied. In this study, we invest...

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Publicat a:BMC Neurol
Autors principals: Zhang, Jing, Jiang, Huawei, Shao, Jiaofang, Mao, Ruifang, Liu, Jie, Ma, Yingying, Fang, Xuefeng, Zhao, Na, Zheng, Shu, Lin, Biaoyang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233052/
https://ncbi.nlm.nih.gov/pubmed/25366337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-014-0207-y
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