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Maduramicin arrests myocardial cells at G(0)/G(1) phase of the cell cycle through inhibiting AKT-Cyclin D1 signaling
Maduramicin, a polyether ionophore antibiotic used as an anticoccidial feed additive in poultry, is toxic to animals and humans and can cause heart failure. The present study was initiated to explore the underlying mechanism of toxicity in H9c2 myocardial cells. We observed using cell imaging and co...
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| Udgivet i: | 3 Biotech |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer International Publishing
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8215011/ https://ncbi.nlm.nih.gov/pubmed/34221817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-021-02894-6 |
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