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Maduramicin arrests myocardial cells at G(0)/G(1) phase of the cell cycle through inhibiting AKT-Cyclin D1 signaling

Maduramicin, a polyether ionophore antibiotic used as an anticoccidial feed additive in poultry, is toxic to animals and humans and can cause heart failure. The present study was initiated to explore the underlying mechanism of toxicity in H9c2 myocardial cells. We observed using cell imaging and co...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:3 Biotech
Päätekijät: Chen, Xin, Liu, Chang, Zhang, Meng, Zhang, Yumei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer International Publishing 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215011/
https://ncbi.nlm.nih.gov/pubmed/34221817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-021-02894-6
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