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Straightforward Access to Hexahydropyrrolo[2,3-b]indole Core by a Regioselective C3-Azo Coupling Reaction of Arenediazonium Compounds with Tryptamines

A base-mediated regioselective electrophilic addition of arenediazonium salts at the C3-position of tryptamines followed by cyclization provides an efficient entry to C3-nitrogenated hexahydropyrrolo[2,3-b]indoles (HPIs) that can subsequently be transformed into 3-arylhexahydropyrrolo[2,3-b]indoles...

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Detalles Bibliográficos
Publicado en:European J Org Chem
Autores principales: Stephens, David E., Larionov, Oleg V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233011/
https://ncbi.nlm.nih.gov/pubmed/25408620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201402088
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