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Organocatalytic asymmetric selenofunctionalization of tryptamine for the synthesis of hexahydropyrrolo[2,3-b]indole derivatives

A chiral phosphoric acid-catalyzed selenofunctionalization of tryptamine derivatives provides access to 3a-(phenylselenyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole derivatives in high yields and with synthetically useful levels of enantioselectivity (up to 89% ee).

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Bibliografiske detaljer
Main Authors: Wei, Qiang, Wang, Ya-Yi, Du, Yu-Liu, Gong, Liu-Zhu
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740605/
https://ncbi.nlm.nih.gov/pubmed/23946855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.177
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