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Herpes simplex virus serotype and entry receptor availability alter CNS disease in a mouse model of neonatal HSV

BACKGROUND: Outcomes of neonates with herpes simplex virus (HSV) encephalitis are worse after infection with HSV-2 when compared with HSV-1. The proteins herpes virus entry mediator (HVEM) and nectin-1 mediate HSV entry into susceptible cells. Prior studies have shown receptor-dependent differences...

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Detalhes bibliográficos
Publicado no:Pediatr Res
Main Authors: Kopp, Sarah J., Ranaivo, Hantamalala Ralay, Wilcox, Douglas R., Karaba, Andrew H., Wainwright, Mark S., Muller, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233006/
https://ncbi.nlm.nih.gov/pubmed/25198371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2014.135
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